Yes, Deso offers a few more options than Yampa/Lodore. But both are available if you go pre or post season, or are willing to pick up cancellations on short notice. The bummer is when you score a Yampa permit or invite, and then get a Lodore invite also. Then you have to choose, as you can't really do both.
I'm not sure which system I like the least.....the Yampa/Lodore lottery or the PITA call-in for Deso. I have parked myself on the phone between 7:45am and 8:00am for many days in a row, only to hear the busy signal over and over again.
To the OP..... if you get on a Lodore trip, try to stay at Jones Hole. Nice camp, fly fishing stream, and the infamous "Butt Plug" Falls a short hike upstream. Also check out Whispering Cave in Echo park where the Yampa comes in.
KJ