Ask your boat manufacture what they recommend.
I know AIRE has said not to use it to much. I use it in the fall. I clean the boat (clean zippers and wash bladders with running water. Then clean with a rag and water, 303 liberally. let the boat completely dry out, suction / vacuum any water out of chambers, blow out PRV with air hose, shake on baby powder, roll tight as a drum.
In the spring, I like to apply some zoggs or sticky bumps "cold water" surf wax to the top of the chambers for the first few runs.
I think to much 303 would be bad. But it is good on tires, car interiors, rubber gaskets, trampoline pads and mats, and anything else that spends its time in the sun and is made of oil based rubber or plastic.
Claimer: Someone that makes a claim that they have been there and done that, can do anything you can do better than you. I hate "claimers"