Lower Yough is an easy read and run class III. I used to guide there back in the mid 90's. Somewhat of a zoo with all the rafts. There is a two mile section of river known as "the loop" that puts you roughly 1/2 mile from where you started (Loopegheny). And you can do laps there all day and walk back to town.
There is a fee for putting on the river and it is controlled by the parks. When I was there it was $2.50 and that included a bus ride to a parking area at the take out if you want to run the full 7 or 8 miles.
The falls in Ohiopyle (Class IV) are still illeagle to run but are easy if you happen to "miss" the take out for the Middle Yough (Class II which I have never run) the fine for running the falls is something like $1500. Over the falls race is in August! Sweet!
If you are an advanced boater, I recomend the 45min drive to Friendsville, Maryland to run the Upper Yough. There are regular releases on many weekends including mondays and Fridays. Speak to the locals. This is a classic PA creek roughly class IV.
If it happens to rain a lot check out Meadow Run in Ohiopyle and the Bear Creek in Friendsville.
The paddle community is very mid-west and easy going always willing to have an extra along.
Say so long to the steep, beefy, cold water of the west and enjoy the warm, channelized, pool drop rivers of of the east!
Remember, if it rains check the gauges!