Lots of stuff to do and lots of it is as good as anywhere too.
Cal Salmon, Scott, Smith, Sacramento, South Umpqua, Illinois & Upper Trinity runs
Some year round
Upper, Middle and Lower Klamath, Middle Rogue, Lower Rogue, NF Rogue & North Umpqua & Lower Trinity
All of these are do-able as day trips from the Rogue Valley, but this is big country with very few roads that take a direct route so looong days are the norm
By looking at AW's river data base you should be able to get at least a little beta on all of these runs. There are other resources I be glad to list if you're interested.