I drive from NW Denver to Boulder a couple times a week. I head up Sheridan to 36, and then into Boulder. I leave around 8:15-8:30 and it takes about 35-40 minutes. The traffic is usually pretty light.
RTD options are pretty good. The B express leaves downtown Denver every 30 minutes in the morning and gets to Table Mesa in about 30 minutes. I hop off and bike to my office from there, but I know it continues on and swings up and over the hill by campus. www.rtd-denver.com
will have specific route details.